Former three-time UFC title challenger Chael Sonnen has failed a random, pre-fight drug test from the Nevada State Athletic Commission and has been removed from UFC 175 in July.

Sonnen was originally expected to square off with his opposing The Ultimate Fighter: Brazil 3 coach, Wanderlei Silva, at the event, but Silva was replaced by former UFC champion Vitor Belfort less than two weeks ago. Ironically, it was Belfort who was expected to face difficulties in getting a license from the NSAC based on a past failed test of his own.

The positive test revealed two banned antiestrogenic substances in Sonnen’s system: Anastrozole, used to treat breast cancer, and Clomiphene, used for female infertility.

The 37-year-old was one of the first fighters to bring testosterone-replacement therapy (TRT) into the limelight after his UFC 117 loss to Anderson Silva. Sonnen was suspended by the California State Athletic Commission following the fight. However, since that time, the treatment has been banned in Nevada and many other states. The Oregon fighter is just 1-3 over his last four appearances inside the Octagon and is expected to be suspended and fined by the NSAC for his failed test.

The UFC has acknowledged the failed test and stated that Sonnen would address the situation later today.

UFC 175 takes place from the Mandalay Bay Events Center on Saturday, July 5. It will be headlined by a middleweight title fight between champion Chris Weidman and former light heavyweight kingpin Lyoto Machida. The night’s co-main event features a women’s bantamweight title fight between Ronda Rousey and Alexis Davis.

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