UFC 173 has a co-main event as former heavyweight champion Junior dos Santos will square off with fellow top 10-ranked fighter Stipe Miocic on May 24.

Dos Santos enters the contest on the heels of a second defeat to current champion Cain Velasquez. The Brazilian defeated Velasquez by first-round knockout at the UFC’s first event on Fox in November of 2011, but was thoroughly dominated in the rematch at UFC 155 and the rubber match at UFC 166 in October. The 29-year-old is considered one of the heavyweight division’s best strikers, having stopped 12 of his 16 wins via strikes.

Across the cage will be once-beaten Stipe Miocic. The Ohio-based fighter of Croatian decent has steadily climbed up the heavyweight ladder, topping veterans Roy Nelson and Gabriel Gonzaga in his last two Octagon appearances. The 31-year-old former collegiate baseball player and wrestler’s lone loss came against Stefan Struve in the main event of UFC on Fuel TV 5 in late 2012. His recent wins have pushed his record to 5-1 within the promotion.

UFC 173 takes place from the MGM Grand Garden Arena in Las Vegas. It will be headlined by a middleweight title fight between current champion Chris Weidman and former UFC light heavyweight champion Lyoto Machida. Machida recently replaced another former champion and fellow Brazilian, Vitor Belfort, after the Nevada State Athletic Commission revealed that it had banned therapeutic-use exemptions for testosterone-replacement therapy (TRT).

The night’s main card will air live on pay-per-view. The preliminary card is expected to be split between a broadcast on Fox Sports 1 and a live stream on the promotion’s digital network, UFC Fight Pass.

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